What if professional learning were intentionally designed to mirror how the brain learns best? In this thought-provoking session, participants will dive into cutting-edge research from neuroscience and cognitive science to explore how emotion, memory, and cognition work together to shape learning. This experience blends the science of learning with the promise of artificial intelligence (AI), offering educators powerful insights and tools to reimagine how professional development can look, feel, and function. Together, we will examine the implications of brain-based research for designing high-impact professional learning—exploring how AI can personalize growth pathways, elevate reflective practice, and support data-informed instructional decisions. Participants will also consider how learning environments, teacher expectations, and school systems can be restructured to align with how adults and students learn most effectively. Rather than prescribing one-size-fits-all answers, this session equips educators and leaders with new lenses to analyze challenges and innovate solutions that are responsive to their own professional contexts.